Chemistry & Analytics

3BP’s chemistry unit was set up to efficiently run iterative rounds of peptide optimization with excellent turnaround times.
Our extensive mass-spectrometry and HPLC equipment is optimally integrated in our R&D workflows to support multiple projects in parallel. Important compound properties can be readily assessed and provide synthesis chemists with immediate decision support.

Diverse collection of building blocks. 3BP owns an outstanding collection of non-natural proprietary amino acids and building blocks for peptide- and peptidomimetic chemistry. We can thus create more diverse compound sets and accelerate the overall optimization process. Furthermore, the compound collection supports the generation of new intellectual property. Successfully securing patent claims requires a comprehensive and data-driven understanding of the structure-activity relationships and is essential for maximizing the value of drug discovery projects.

Versatile conjugation chemistry. Our chemistry group has extensive experience with site specific conjugation chemistry, (e.g. PEG-conjugation and analytics), metabolite ID, and PK-studies.

We have already delivered several therapeutic product candidates and two purification ligands for undisclosed therapeutic proteins to our partners.